Sheriff's deputies received a call from the hikers at about 8:30 p.m. Monday night that they were trapped in a drop-in cave, the Sheriff's Department said.
The cave is in the 3000 block of McCain Valley Rd. in Boulevard, east of Pine Valley.
The three were not able to climb out, and the male hiker has an injured shoulder, authorities said.
Due to the power lines in the area, emergency personnel could not dispatch a helicopter to pull them out.
A search and rescue team will drop a cache of food and supplies into the cave, and the three hikers will spend the night until crews can respond in the morning.
Deputies plan to request a rescue team from San Bernardino Sheriff's Department to respond Tuesday morning.
Source: NBC San Diego